Pretreatment method for determination of carbopol and olaquindox metabolite residues in milk and milk powder

Carbadox and Olaquindox are both quinoxaline compounds. These drugs have a significant effect on promoting animal growth and are used as feed additives for pigs and other farmed animals. Both of them have potential teratogenic and carcinogenic effects, and their metabolites may also bring health risks. Therefore, many countries have listed carbachol and olaquindox as banned or restricted drugs for food animals. Chloroline-2-carboxylic acid (QCA) and 3-methylquinoxaline-2-carboxylic acid (MQ-CA) set limits for residue monitoring.

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