Inhaled administration has long been a critical non-invasive method for delivering medications, especially in the treatment of respiratory conditions such as asthma and chronic obstructive pulmonary disease (COPD). Over the past few years, with the rapid advancement of the biopharmaceutical industry, inhalation has emerged as a promising route for both local and systemic delivery of biotech drugs that suffer from poor oral bioavailability—such as peptides, proteins, and nucleic acid-based therapeutics. This growing interest has led to increased research and development focused on optimizing drug formulations for inhalation.
This book compiles key literature and application notes from Malvern, focusing on the characterization of particles used in inhalation therapy. It serves as a valuable resource for researchers and professionals currently working on inhalation studies. Whether you're developing new drug delivery systems or evaluating particle properties, this collection offers insights into best practices and cutting-edge technologies.
The following Malvern instruments are discussed in this publication:
- **Mastersizer 3000/2000**: A laser diffraction particle size analyzer ideal for measuring the size distribution of dry and wet powders.
- **Spraytec**: A real-time spray particle size analyzer that provides instant feedback during nebulization or aerosol generation.
- **Morphologi G3**: A dry particle size and shape analyzer designed for detailed morphological analysis of particulate samples.
- **FPIA-3000**: A wet particle size analyzer that measures particle size in liquid suspensions with high accuracy.
- **Morphologi G3-ID**: Combines particle size, shape, and chemical composition analysis, offering a comprehensive approach to particle characterization.
If you'd like access to the full-text articles referenced in this document, feel free to contact Wendy at your convenience. We hope this resource proves helpful in advancing your work in inhalation science and drug delivery.
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