Inhaled administration is a crucial non-intravenous method of drug delivery, widely used in the treatment of respiratory conditions like asthma and chronic obstructive pulmonary disease (COPD). Over the past few years, with the rapid advancement of the biopharmaceutical industry, inhalation has become an increasingly important route for delivering biotech drugs that have poor oral bioavailability—such as peptides, proteins, and nucleic acids. This approach allows for both localized and systemic drug delivery, making it a valuable option for a wide range of therapeutic applications.
This book compiles key literature and application notes from Malvern on the characterization of particles used in inhalation therapy. It serves as a valuable resource for researchers and professionals conducting studies in this field. Whether you're working on formulation development, particle engineering, or performance evaluation, the insights provided here can help enhance your understanding and optimize your processes.
The following Malvern instruments are mentioned in this document:
- **Mastersizer 3000/2000**: A laser diffraction particle size analyzer used for measuring particle size distribution in suspensions and dry powders.
- **Spraytec**: A real-time spray particle size analyzer designed for monitoring droplet size during nebulization or aerosol generation.
- **Morphologi G3**: A dry particle size and shape analyzer that provides detailed morphological data on individual particles.
- **FPIA-3000**: A wet particle size analyzer ideal for analyzing particles in liquid formulations.
- **Morphologi G3-ID**: Combines particle size, shape, and chemical composition analysis using advanced imaging and spectroscopy techniques.
If you'd like to access the full-text literature referenced in this guide, please send an email to **wendy** for more information. We hope this resource proves useful in your research and development efforts. Thank you for your interest in inhalation drug delivery!
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